JICDRO is a UGC approved journal (Journal no. 63927)

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Year : 2015  |  Volume : 7  |  Issue : 1  |  Page : 85

News in Dentistry

Ex-Managing Editor, Journal of the International Clinical Dental Research Organization

Date of Web Publication18-Mar-2015

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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2231-0754.153508

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How to cite this article:
Melath AJ. News in Dentistry. J Int Clin Dent Res Organ 2015;7:85

How to cite this URL:
Melath AJ. News in Dentistry. J Int Clin Dent Res Organ [serial online] 2015 [cited 2019 Jun 24];7:85. Available from: http://www.jicdro.org/text.asp?2015/7/1/85/153508

   Periodontal Disease could Lead to New Issue ! Top

Periodontal disease results in a newly discovered problem when it is not treated properly.

Byproducts of bacteria in gum disease, known as metabolic small chain fatty acids, can cause HIV in dormant T-cells to become active and cause the virus to replicate, according to a research team from Case Western Reserve University.

This research shows why people with HIV infections and periodontal disease have higher levels of the virus in their saliva when compared to HIV patients who have healthy gums. It's possible that the byproducts from other bacteria infections could alter gene expression for the same reason.

In the interaction between gum disease and HIV, five SCFA byproducts that come from two oral bacteria result in activating resting immune T-cells. Researchers explained this process as using jumper cables to restart a dead battery.

The researchers pinpointed butyric acid as something that reactivates the virus associated with Kaposi's sarcoma, which happens to be the most common malignancy in HIV patients. But when all of the SCFA byproducts work together, the results can be similar compared to when butyric acid works alone.

HIV antiviral therapy thwarts active HIV cells from replicating and has no impact on the quiet viruses in sleeping T-cells. Therefore, if patients don't have gum disease, the virus sleeps and doesn't cause any problems.

As published in the journal: "Virology"

   Tooth Loss May Lead Reduction in Walking Speed and Memory Loss in Adults ! Top

When a person loses his or her teeth, it only gets worse from there. A new study indicates that the memory and walking speed of adults without teeth decline at a higher rate when compared to those who still have their teeth.Study was conducted by University College London There were 3,166 adults who took part in the study and their performance in memory and walking speed was tested. The results showed that people with none of their own teeth performed approximately 10 percent worse in those areas when compared to people with teeth.

The correlation between tooth loss and memory was rationalized after the results were adjusted for factors like sociodemographic characteristics, existing health problems, overall health, smoking, drinking, depression, and a few other factors. Even after all of the factors were taken into account, people without teeth still walked at a slower rate compared to people with teeth.

The drastic differences between the people with teeth and without were more profound in adults aged 60 to 74 than those aged 75 and older. The study also pinpointed wealth and education as two of the largest factors in prohibiting tooth loss.

The study concluded that recognizing excessive tooth loss provides the chance to pinpoint adults who are a higher risk for a rapid mental and physical decline later in life. This is especially vital when there are factors that could be altered to lower the chance of excessive tooth loss and health decline.

As published in the "Journal of the American Geriatrics Society"

   Possibly A Permanent Solution to Dentinal Hypersensitivity . . . Top

A biomaterial was created that has the potential to rebuild worn enamel and lower tooth sensitivity for an extended time. This will be helpful for people with sensitivity. The material was tested on dogs and Tooth sensitivity is a common issue among dental patients. It can lead to major dental problems, in addition to the pain it causes. The problem develops after a tooth's enamel degrades, leaving tiny, porous tubes and allowing underlying nerves to be susceptible to extreme temperatures.

Some current treatments, like special toothpastes, work by blocking the openings of tubes. The seal created is only temporary and doesn't hold up to the wear and tear of brushing and chewing. That's why the research team set out to look for a method that could be a long-term solution.

The researchers created a type of paste based on elements in teeth, particularly calcium and phosphorus. The paste was tested on dogs' teeth and the research team determined that it closed up tubes in a deeper fashion compared to other treatments. This depth could be the key to a lasting solution to the problem and rebuilding enamel.

As published in the journal: "ACS Nano"


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