Journal of the International Clinical Dental Research Organization

REVIEW ARTICLE
Year
: 2019  |  Volume : 11  |  Issue : 1  |  Page : 3--8

Role of Interleukin-17 in immunopathology of chronic and aggressive periodontitis


Anand Narayanrao Wankhede1, Prasad Vijayrao Dhadse2 
1 Department of Periodontology, V.Y.W.S Dental College and Hospital, Amravati, India
2 Department of Periodontology, Sharad Pawar Dental College and Hospital, Wardha, Maharashtra, India

Correspondence Address:
Dr. Anand Narayanrao Wankhede
V.Y.W.S. Dental College and Hospital, Amravati, Maharashtra
India

Interleukin-17 (IL-17) is a pro-inflammatory cytokine which is derived from T-cells. It is a strong agent of inflammation in inflammatory condition including the periodontitis. Several studies have focused on finding the role of IL-17 in the initiation and progression of chronic periodontitis and aggressive periodontitis (AgP). The aim of this review is to analyze the role of IL-17 in immunopathology of chronic periodontitis and AgP. An electronic literature search was conducted in the PubMed database using keywords aggressive, chronic, cytokine, IL-17, and periodontitis. A total of 152 publications were identified, wherein 43 studies fulfilled the inclusion criteria which were included and data extraction was done. Findings of these studies indicate that IL-17 is the important cytokine which plays a crucial role in the initiation and progression of periodontitis. More studies in all ethnic groups are necessary and hence that the predictive value (cutoff) of IL-17 levels in chronic and AgP can be determined.


How to cite this article:
Wankhede AN, Dhadse PV. Role of Interleukin-17 in immunopathology of chronic and aggressive periodontitis.J Int Clin Dent Res Organ 2019;11:3-8


How to cite this URL:
Wankhede AN, Dhadse PV. Role of Interleukin-17 in immunopathology of chronic and aggressive periodontitis. J Int Clin Dent Res Organ [serial online] 2019 [cited 2019 Jul 17 ];11:3-8
Available from: http://www.jicdro.org/article.asp?issn=2231-0754;year=2019;volume=11;issue=1;spage=3;epage=8;aulast=Wankhede;type=0